Genotoxicity of 4-monochlorobiphenyl in the lung of transgenic male 344 Fisher rats
نویسندگان
چکیده
statistical advice and assistance. Thank you to my advisor and committee for their assistance and input. Thank you to my parents Mike and Lisé and my sisters Rachel, Bridget, and Lucy for all their support.
منابع مشابه
4-monochlorobiphenyl (PCB3) induces mutations in the livers of transgenic Fisher 344 rats.
4-monochlorobiphenyl (PCB3) is found in small amounts in commercial PCB mixtures, indoor and outdoor air, and in food. In contrast to highly chlorinated congeners that are more resistant to metabolic attack, PCB3 is more readily converted by xenobiotic-metabolizing enzymes to monohydroxy-PCBs and further to dihydroxy-metabolites, which can be oxidized to quinones. Our recent studies demonstrate...
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